NRAS Logo
Logged in as: pedro-pmc Search | Moderate | Active Topics | My Profile | Members | Logout

New Topic Post Reply
Is This Why I Have RA? Options
Paula-C
#1 Posted : Tuesday, May 04, 2010 3:58:49 PM Quote
Rank: Advanced Member


Groups: Registered

Joined: 12/3/2009
Posts: 838
Location: Nottinghamshire
The forum is not very busy at the moment so I thought I would tell you about my interesting telephone conversation this morning and give you all something to think about.

When I was 6 I had encephalitis which is inflammation of the brain. This was a result of measles (mums of babies take note of how serious a childhood illness can be and get your babies immunised against it) My parents have aways told me that at the time they were told that I had a 50/50 chance of survival and if I did survive I would of had some sort of brain damage. I was addmitted to an isolation hospital and I was in coma for two weeks. Obvioulsy I have made a full recovery.

Since then, up until being diagnosed with RA I have been very healthy. I've always thought that I must have a super duper immune system, and when I got DX with RA, I thought it must of got a bit bored and decided to attack me.

At the moment even though all of my blood test are 'normal' I am having more pain than normal and my over active brain's been thinking. Did they give me some sort of drug when I was so ill to bring my inflammation levels down in order to save my life and did this in some way alter what my normal inflammations levels should be. Told you my brain is very active didn't I?

After a short search on google I got the phone number of a help line for encephaltis. I spoke to someone today. Now when I first got DX with RA and I was asked all of the normal questions I mentioned the fact that I had had encephalitis. The consultant never said anything. Well, I have been told today that there is a link, they are both connected with the immune system. There is two sorts of encephalitis and I would of had the post encephalatis and not a viral one, the latter being the worse one to have. That must be why my parents were told that I had a 50/50 chance, I am assuming that 46 years ago the understanding of the illness was not like it is now.

I have got an over reactive immune system, thats what the lady today told me and when I caught measles it must of gone into overdrive and attacked my brain. Apparently wait for this folks.............my ancestors must of lived in large communities where disease was rife and through the generations their immune systems had to be good to cope with all the illness, basically the ones without a good immune system would die. This has been passed down to me, but nowadays there is not so much disease around so my over reactive immune system decided to attack me (does make a bit of sense especially when it can be passed down from parents). I said that if that was the case then surely through the years only the one's with the good immune system would survive, so everyone would then have RA. No........if someone married someone who didn't have such a good immune system (the posh people) this would then be watered down. If thats the case then, I must come from poor people.

She said that my immune system goes in peaks and troughs and if something triggers it then it gets over reactive again (like measles when I was 6). The consultant did ask if I had any illness, operations or truauma before I had the symptons of RA. I did have alot of stress and upset when Julie left to live in Spain and he said that was probably the trigger that started the RA.

So there you are............I have my ancestors to thank for the wonders of RA

Paula
jenni_b
#2 Posted : Tuesday, May 04, 2010 6:54:01 PM Quote
Rank: Advanced Member


Groups: Registered

Joined: 12/3/2009
Posts: 2,237
Location: nr Southampton
Hi

My rheummy explained that we have immune systems that have fought a million bugs and plagues etc over the centuries and survived.

if you think about it, our ancestors must have survived bubonic plague.

BUT that does go for every single person on the planet.

As for RA, there is a link to NOrth America- who still have the highest population with the condition in the world. It wasnt until the 16th-17th centuries that it took a- hold in Europe, when the immune system from the colonies were well and truly mixed with Europeans.

(small claim to fame coming up)
I discovered the earliest record of RA nras knows about. It is in Caravaggio's painting of cupid. he chose the model of a young boy with salo skin, thought to have....yep! Rheumatoid arthritis.
carravagio's cupid

Certainly, discussing the complex immune pictures of old ancestry reveal why there is such problems treating RA. No one's immune system is the same as we all have different ancestry with some common elements.

It also remains that one persons RA is not the same as another. My rheummy thinks that in years to come what we currently know as RA will be divided into dozens of other named conditions. 200 yrs ago all bone and arthritis' conditions were known as gout, then it went to gout and rheumatics etc.

Some drs think you trigger RA when your body fights off a certain virus. Others think it is genetically predisposed, others think it is to do with hormonal surge or stress. I read recently of someone who seemed to get it reacting to a vaccine.

The other thing to add is that one immune system condition can tip into others. If you get one you are more likely to develop others. Diabetes is something to do with immune systems I think.

anyway! Fascinating stuff

Jenni x
how to be a velvet bulldoser
jeanb
#3 Posted : Tuesday, May 04, 2010 7:00:01 PM Quote
Rank: Advanced Member


Groups: Registered

Joined: 12/3/2009
Posts: 3,006
Location: Timperley
Wow - this really is interesting stuff. Some of it makes a lot of sense but I'll have to put my brain in gear and think about it! Thanks both of you for the posts.
FIONA752
#4 Posted : Tuesday, May 04, 2010 7:02:11 PM Quote
Rank: Advanced Member


Groups: Registered

Joined: 12/4/2009
Posts: 312
Dear Paula,
I just read your post with interest.
This ties in with what my Rheumatologist has said to me too.
Basically, that it is thanks to people like us with the "super duper"
immune systems, that their are people like him with "good enough"
immune systems.
Just prior to my getting R.A, 15 years ago my three kids had been really
stressful teenagers and I was divorced and having to cope with it all
on my own for years.
I also think that there is a definate link between coming from disease ridden
places,( my family were nearly wiped out by Tuberculosis in the 19th and early 20th
century in Cornwall), and I had to be vaccinated against it at one day old as my Grandmother
and Great Aunt had nearly died of it. Tuberculosis patients were advized to convalece there so it spread.
The other side of my Mother's family came from London untill the early 20th Century, so
imagine the epidemics they lived through and my Dad from Glasgow.
I think that says it all really - you really did have to be tough to survive.
I had Measles as a child and I remember it as the worst illness I ever had back then.
I needed to wear glasses afterwards and have allways wondered if it damaged my
eyes.
Best wishes,
FionaSmile
BarbieGirl
#5 Posted : Tuesday, May 04, 2010 7:43:05 PM Quote
Rank: Advanced Member


Groups: Registered

Joined: 12/3/2009
Posts: 1,110
Location: London
Wow!! really interesting!!! Makes you think doesnt it? I found my symptoms became more noticable when a little boy I had worked with in school for 4 years passed away from his genetic illness. Maybe this triggered the RA. Although I had lost my mother in 1995, at least she had her life, and was 77 years old, my darling Jordan was only 9. I was completely devastated, and still very much friends with the family who have 2 daughters, one of whom unfortunately has the same disease. Sorry, waffling a bit!!
BARBARA
Julia17
#6 Posted : Tuesday, May 04, 2010 8:19:01 PM Quote
Rank: Advanced Member


Groups: Registered

Joined: 2/18/2010
Posts: 1,098
Location: farningham kent
These posts are very interesting and thought provoking to say the least.

Thanks very much !

Julia
Calmwater22
#7 Posted : Tuesday, May 04, 2010 9:59:49 PM Quote
Rank: Advanced Member


Groups: Registered

Joined: 12/3/2009
Posts: 1,740
Umm thanks for posting very intriguing.

well before i started with RA,we ahd on 1 hand happy carefree childhood adventures etc,had chicken pox though kind things vaccinated so no measles etc.
butf rom early age both grandfathers were ill and passed away before i was 9 years old,at same time 1 gran had RA another gran ahd mental illness this was a great stress on family.
our childhood involved hirin or borrowing a car almost every weekend to visit one of grandparents in hospiatl,psychictric unis or various locations.
mum had nervous breakdown,dad dunk to much.poor working class family.
i devloped severe heyfever age 10.
age 15 by this time developed gynae problems,while at college age 16 both gran step grandad died 2 weeks apart.

age 17 working on old folks home witnessed great many deaths,sad times at same time RA came to me overnight.
between then and now less stress.

could go on but far to much written already.
anyway majpr stress 2005/2006 hubby major surgey liver illness discovered RA surpise surpise comes back full on before this self medicated.
since then alot more family woes,lupus, fibro all diagnsoed during 2009 most difficult year with strained family relatioships.

melly
cuddly cats make my world seem so much more fun
lizziemouse
#8 Posted : Wednesday, May 05, 2010 7:08:36 AM Quote
Rank: Advanced Member


Groups: Registered

Joined: 12/3/2009
Posts: 872
ThumpUp
How interetsing Paula -

Well ~ if we are going to have this inconvenient disease we might as well make it interesting hadn't we!
One day when I'm not so tied into work etc I'm going to do our family tree
I'm even more looking forward to doing it now xx

Huggles!

love Liz xxxxx
Rose-B
#9 Posted : Wednesday, May 05, 2010 9:48:46 PM Quote
Rank: Advanced Member


Groups: Registered

Joined: 4/20/2010
Posts: 1,749
Location: Somerset
Gosh, what interesting thoughts

Certainly makes you think .
dawnybee
#10 Posted : Wednesday, May 05, 2010 10:13:14 PM Quote
Rank: Advanced Member


Groups: Registered

Joined: 12/6/2009
Posts: 67
Hi all, very interesting! I had a hysterectomy after two ovarian cysts. The last cyst i had was as large as a grapefruit and attatched to my bowel. I was so euphoric after op, i was only off work 8 weeks, felt i could run the world and got a new job. This was the worst thing i could have done. I had only been back at work a few months when i changed jobs. The job was very stressful, and not at all like i'd hoped it was going to be. I was also in the early days of HRT after the op.

I left that job, with no job to go to. It was November and just after christmas an old employer contacted me and offered me some hours. I was so happy, but within weeks of starting, th RA started.I often thougth it was the combination of op, HRT, stress of job as well as financial impilcations.

We have now moved premises, and our work is so stressful now we are in a big company and i'm worried i will flare up again.

So....i have to agree, stress and hormones could have had apart to play.

dawnybee
Users browsing this topic
New Topic Post Reply
Forum Jump  
You can post new topics in this forum.
You can reply to topics in this forum.
You cannot delete your posts in this forum.
You can edit your posts in this forum.
You cannot create polls in this forum.
You cannot vote in polls in this forum.

SoClean Theme By Jaben Cargman (Tiny Gecko)
Powered by YAF 1.9.3 | YAF © 2003-2009, Yet Another Forum.NET
This page was generated in 0.422 seconds.